Welcome to the Journal of Prolotherapy

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Featured Article


March 11, 2016

Understanding Mechanical Emulsification (Nanofat) Versus Enzymatic Isolation of Tissue Stromal Vascular Fraction (tSVF) Cells from Adipose Tissue: Potential Uses in Biocellular Regenerative Medicine

Robert W. Alexander, MD, DMD, FICS, Volume 8 : 2016

With rapid growth of experiences and techniques in the field of Biocellular Regenerative Medicine, clinical scientists and biotechnical advancements constantly seek to understand and optimize uses of the multipotent heterogeneous cellular populations found in adipose tissue complex.

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Featured Article


April 1, 2016

Treatment of Trigeminal Neuralgia Utilizing Neural Prolotherapy: A Case Report

Volume 8 : 2016

Neural prolotherapy, as developed by Jon Lyftogt, has been found to be an effective treatment for neurogenic pain syndromes. We report a case of trigeminal neuralgia successfully treated with neural prolotherapy. The patient is a 70-year-old man with a 15-year history of trigeminal neuralgia refractory to pharmacologic treatment. After one treatment of neural prolotherapy the patient reported 5 months of complete resolution of his symptoms. A second treatment was performed affording him another 10 months of relief. Neural prolotherapy may have an important role in treating trigeminal neuralgia. It can be a safe and effective treatment for those experiencing side effects from medications, contraindications to surgery, or less than favorable improvement from traditional treatments.

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Welcome to the Journal of Prolotherapy®


The Journal of Prolotherapy® is a peer-reviewed journal with the purpose of providing the readers with new, cutting-edge information on Prolotherapy, as well as provide a forum for physicians and patients alike to tell their stories.

As of 2012, all issues of the Journal of Prolotherapy are FREE to access online.

Why the Journal of Prolotherapy®?


Our mission is to educate the world about the life-changing effects of Prolotherapy. Like you, we want more people to know that there is hope to get out of chronic pain and that hope is Prolotherapy.

When a person finds out about Prolotherapy for the first time, they often say or think “why haven’t I heard of this before?” JOP is doing their best to make sure everyone in chronic pain has at least heard about Prolotherapy. The skeptics of Prolotherapy often say that research is lacking. To put more of it out there, we continue to print in electronic and paper journal format, the experiences of doctors and patients with Prolotherapy. The whole journal revolves around the regenerative injection technique known as Prolotherapy.

JOP believes that it is important to get both the doctors’ and the patients’ perspectives. We believe that the greatest evidence for the effectiveness of Prolotherapy is not going to come from a “double-blind scientific study” but from the millions of changed lives from Prolotherapy. In essence, almost every patient that gets Prolotherapy proves that Prolotherapy works.

Most folks who get Prolotherapy have a chronic degenerative condition. These conditions are supposed to get worse with time. When such a person receives Prolotherapy and their condition subsequently reverses, as evidenced not only by the relief of pain, improvement in activity level, decrease in medication usage and usage of other health care for their pain, but also by X-ray and MRI improvement, this, in our opinion, is definitive proof that Prolotherapy does, indeed, regenerate structures.

With your help, we hope to continue to change lives. We want to get people back to sports, back to being active and without pain, back to being the kind of people they wish to be! We see hundreds, thousands, even millions of people getting out of pain because they received the life-changing effects of Prolotherapy. We believe that this is a cause worth fighting for! We hope you will join the fight by subscribing to JOP, writing articles, case studies, even your own experience with Prolotherapy, and get others on this crusade. Together educating the world about a successful treatment for chronic pain…and that treatment is Prolotherapy!

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